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Gastrointestinal health program:

Modern breeding industry usually aims at the pursuit of high growth performance of animals. In the format of solutions, the health of gastrointestinal tract is the most concerned. Whether the health of gastrointestinal tract affects the absorption and digestion of nutrients and the growth of animals to the greatest extent.

Generally, there are several factors affecting gastrointestinal health:

1. Pathogenic microorganisms and their metabolites in intestine

2. Intestinal microbial imbalance

3. Antinutritional factor

4. Gastrointestinal pH

5. Mechanical damage

Montmorillonite in the gastrointestinal tract can cover the surface of the intestinal tract with its excellent dispersion performance, protect the gastrointestinal mucosa from damage, and absorb various pathogenic microorganisms and their metabolites. It has the function of relieving diarrhea and mildew, and effectively solves the gastrointestinal health problems of animals.


Nutrient adsorption solution:

Montmorillonite products have good adsorption performance, can adsorb pathogenic microorganisms in gastrointestinal tract, and also can adsorb some nutrients. It is found that montmorillonite has no adsorption effect on vitamin C and methionine, while montmorillonite has a certain adsorption effect on lysine, vitamin B2 and other nutrients that are easy to dissociate into positive ions in solution. The adsorption is a reversible process, and the resolution rate reaches more than 90% under the low concentration of intestinal nutrients.

The adsorption and desorption results of qingmeibao for methionine, lysine hydrochloride, vitamin B2 and vitamin C are shown in the table below.


surface2  Adsorption of nutrients by qingmeibao


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It can be seen from the above table that in the artificial gastric juice, qingmeibao has certain adsorption effect on methionine, lysine hydrochloride and vitamin B2, but basically has no adsorption effect on vitamin C; however, in the artificial intestinal juice, the nutrients combined by qingmeibao, such as methionine, lysine hydrochloride and vitamin B2 More than 90% of them are desorbed, so the use of qingmeibao will not reduce the utilization rate of these nutrients in the process of production and application.


Aspergillus flavus solution:

Aflatoxin exists in soil, plants and animals, all kinds of nuts, especially easily contaminating peanut, corn, rice, soybean, wheat and other food and oil products. It is a kind of mycotoxin with the greatest toxicity and the most prominent harm to human health.

Aflatoxin poisoning is mainly harmful to the liver of animals. The results show that aflatoxin can lead to the decrease of liver function, the decrease of milk production and egg production rate, the decrease of immunity of animals, the infection of harmful microorganism, the atrophy of bursa of Fabricius and chest gland, hypodermic hemorrhage, poor reaction, the decrease of resistance, the failure of vaccine, the decrease of egg size and yolk weight Low quantity, low fertilization rate and hatching rate, increased and unhealthy embryo death, slow growth of livestock, decreased feed rate, jaundice, rough fur, hypoproteinemia, liver cancer and immunosuppression.

In addition, long-term consumption of feed containing low concentration of aflatoxin can also lead to intraembryonic toxicity. Generally, young animals are more sensitive to aflatoxin. Aflatoxins can not only reduce the milk production of dairy cows, but also make the milk contain the transformed aflatoxins M1 and M2. If these milk is drunk by people, it will greatly harm the health and safety of human body.

Affected objects: poultry, livestock, cattle, sheep, horses, etc.

Main hazards: reduce immunity, weaken liver detoxification, cause cancer, rough fur, reduce dairy products, reduce egg production rate, slow growth, etc.

Montmorillonite products have excellent adsorption effect on aflatoxin. Because of the structure and polarity of aflatoxin, it is very easy to be adsorbed by montmorillonite. The use of montmorillonite to solve aflatoxin has been widely recognized in the industry.


surface2 Adsorption of AFB1 by qingmeibao


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It can be seen from the above table that: the product of qingmeibao has a very high adsorption capacity for AFB1, which can reach more than 95% of the adsorption rate, and has a significant improvement compared with ordinary montmorillonite. Qingmeibao can effectively alleviate the inhibitory effect of AFB1 on the immune system of animals and reduce the toxic and side effects of AFB1 on animals.

Zearalenone solution:

Zearalenone is the metabolite of zearalenone, which mainly contaminates corn, wheat, rice, barley, millet and oats.

Zearalenone has estrogen like effect, which can cause acute and chronic poisoning, abnormal reproduction function and even death of animals, abortion, stillbirth and teratogenesis of animals in breeding period, and cause huge economic losses to animal farms.

Qingmeibao Z has greatly purified the adsorption layer of Aluminosilicate by adopting the technology of "nano ultrafine powder purification", which is helpful to increase the adsorption sites of the combination of aluminosilicate and mycotoxin; and "nano ultrafine activation modification" technology, It greatly increased and changed the amount and distribution of charge between the layers of aluminosilicate, changed the malpractice that natural aluminosilicate only adsorbed strong polar mycotoxin, and greatly improved its adsorption and detoxification ability to weak polar Fusarium toxin. Qingmeibao Z has a good adsorption effect on zearalenone.

surface3 Adsorption of Zen by qingmeibao


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It can be seen from the above table that the adsorption effect of ordinary montmorillonite on Zen is very poor, while that of qingmeibao on Zen is good, especially that of qingmeibao qingmeibao Z on Zen can reach more than 90%.
Qingmeibao can effectively absorb Zen toxin, reduce the harm of Zen to mammalian reproduction, reduce the side effects of zearalenone on reproductive system and embryo of breeding animals, and alleviate the inhibitory effect of animal immune system.

Vomit solution

Vomit toxin, also known as deoxynivalenol, mainly contaminates Cereals, followed by oilseeds.

Vomit toxin is very toxic to both human and animals. It can cause vomiting, diarrhea, skin irritation, refeeding, nervous disorder, abortion, stillbirth and so on. Pigs are the most sensitive animals to vomit toxin, followed by poultry, ruminants have the strongest endurance due to the role of rumen microorganisms.

Qingmeibao Z has greatly purified the adsorption layer of Aluminosilicate by adopting the technology of "nano ultrafine powder purification", which is helpful to increase the adsorption sites of the combination of aluminosilicate and mycotoxin; and "nano ultrafine activation modification" technology, It greatly increased and changed the amount and distribution of charge between the layers of aluminosilicate, changed the malpractice that natural aluminosilicate only adsorbed strong polar mycotoxin, and greatly improved its adsorption and detoxification ability to weak polar Fusarium toxin. Qingmeibao Z has a good adsorption effect on vomit toxin.


Table 4 adsorption of Don by qingmeibao


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It can be seen from the above table that: ordinary montmorillonite has basically no adsorption effect on don, while qingmeibao Z has better adsorption effect on don, which can reach more than 80%.

Qingmeibao Z can effectively absorb don toxin, relieve the symptoms of vomiting and refusal to eat, and reduce the damage caused by Don to animal body!

Mycotoxin detection and evaluation program

The detection methods of mycotoxins are increasing day by day: from the earliest thin-layer chromatography to chromatography, enzyme-linked immunosorbent assay, high-performance liquid chromatography and so on.

Generally, there are a large number of samples tested in feed factories. Generally, colloidal gold immunochromatography is used to determine whether mycotoxins in feed meet the limit standard. At present, the detection technology is gradually mature, and there are more and more rapid detection reagent cards on the market, which greatly facilitates the monitoring of mycotoxins in feed by feed enterprises. For more accurate measurement of mycotoxin content, most enterprises choose enzyme-linked immunosorbent assay and high performance liquid chromatography. The state also has the corresponding standards for the detection of mycotoxins in feed.

The evaluation method of mycotoxin adsorbent has not been unified in the industry. Most enterprises are generally divided into two aspects for evaluation: one is in vitro system evaluation, the other is in vivo system evaluation.

In vitro system evaluation: add mycotoxin into buffer solution, add mycotoxin adsorbent, and test the effect of mycotoxin adsorbent by shaking centrifugation. This evaluation method is relatively simple, and the evaluation of product adsorption capacity is relatively intuitive. (if you need a detailed evaluation method of in vitro system, you can consult the R & D Department of Zhejiang sanding Technology Co., Ltd. and we can provide necessary technical support and appropriate testing services.)

In vivo evaluation: many breeders believe that whether mycotoxin adsorbent has effect or not depends on whether the symptoms of the body are relieved. In the existing farms that have been damaged by mycotoxin, the mycotoxin adsorbent product is added to the moldy feed. After feeding for a period of time, the symptoms of mycotoxin disappear, so it is considered that the mycotoxin adsorbent product has the effect of mildew removal.

Table 5 below is the experimental data of detoxification of our products in broilers.

Table 5  Effect of montmorillonite on growth performance of broiler


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Note: the same letter in the same column represents no significant difference (P & gt; 0.05); different letters in the same column represent significant difference(P<0.05).

It can be seen from the above table that: compared with the blank group, the growth performance of broilers would be significantly inhibited if they were fed with aflatoxin at 7-21d, such as reducing the daily gain and growth rate of broilers; the daily gain and growth rate of broilers increased from 13.47 and 2.96 to 13.58 and 3.00 respectively when adding common montmorillonite, which shows that adding common montmorillonite can alleviate the toxicity of AFB1 to broilers to some extent The daily gain of qingmeibao Z was significantly the same as that of the blank group, and the growth rate was higher than that of the blank group, which showed that qingmeibao Z could significantly alleviate or even eliminate the effect of AFB1 on the growth performance of broilers.

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